Melatonin and Insomnia: Beware of Cardiovascular Risks

Melatonin is often used as a natural solution against insomnia. However, a new study from the American Heart Association (AHA) warns about its potential effects on the heart when it is consumed over a long period.

Can melatonin affect the heart?

The study followed 65,000 adults with insomnia, comparing those who had a melatonin prescription for more than one year with those who did not take it.

Result: melatonin users showed an 89% higher risk of heart failure, including hospitalizations and mortality, over a five-year period.

Although the study does not establish a direct cause-and-effect relationship, these findings highlight the need to reassess the cardiovascular safety of this supplement when used chronically.

How does melatonin work in the body?

Melatonin is a neurohormone that regulates the sleep-wake cycle. It is naturally secreted 1 to 3 hours before sleep, activating receptors in the brain to facilitate falling asleep.

But melatonin also acts on other organs, including the heart, through the presence of specific receptors. These interactions can influence:

• Circadian biological rhythm

• Antioxidant and immune functions

• General functioning of certain organs

To date, the long-term effects of high or prolonged doses remain poorly understood, which justifies caution.

What do experts say about its use?

• Short-term use: recommended, only for a few months.

• High or prolonged doses: caution, as long-term benefits and potential risks remain uncertain.

• Specific indications: jet lag, insomnia in adults over 55, and sleep disorders in some children (autism spectrum disorders).

Experts emphasize that melatonin should not be treated as a harmless product, and more clinical studies are needed to better understand its risks.

Precautions and recommendations

• Avoid long-term use without medical supervision.

• Consult a doctor before taking melatonin if you have heart problems.

• Favor natural sleep strategies: consistent bedtime routine, dark and quiet bedroom, comfortable and breathable bedding.
  
  

Conclusion

While melatonin can be effective against insomnia, chronic use may increase the risk of heart failure. Caution is essential, and it is better to prioritize natural solutions and medical guidance to improve sleep.

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